Patrick Taylor

49ers RB Isaac Guerendo (foot, hamstring) did not practice all week and is out for Sunday s game vs. the Dolphins. It sounds like it s the hamstring that s sidelining him. Guerendo s absence leaves San Francisco down to RBs Patrick Taylor, Ke Shawn Vaughn, and Israel Abanikanda. Taylor is the favorite for work, but it s unclear exactly what this backfield will look like. It s also a tough matchup against a Dolphins defense that s limited opposing RBs to 2.8 yards per carry over the last five weeks. See where Taylor sits in the Week 16 RB Rankings.

Taylor is preparing for a larger role with fellow running back Isaac Guerendo (hamstring/foot) ruled out for Sunday's game at Miami, 95.7 The Game reports.

Patrick Taylor is the next man up for Kyle Shanahan and the 49ers. He was the only back other than Guerendo to see an offensive snap last week, though he didn't earn a touch. We could also see Israel Abanikanda and Ke'Shawn Vaughn, though Taylor is the clear starter. The deeper into the depth chart San Francisco goes the harder it is for fantasy managers to trust their starting running back. Still, Taylor is the starting running back for a Shanahan offense that is still clinging to the slimmest of playoff odds. He narrowly cracks the top 24 at his position this week.

Hamstring injury After losing RBs Christian McCaffrey, Jordan Mason and Elijah Mitchell to season-ending injuries, it now looks as if the 49ers will be without RB Isaac Guerendo for Sunday s game vs. Miami. Guerendo is dealing with a hamstring injury and is unlikely to play, per source. (Adam Schefter on X) FF Today's Take: The 49ers suffer yet another injury at the running back position. Patrick Taylor is next up on the depth chart and should get the bulk of work against the Dolphins. Ke Shawn Vaughn and Israel Abanikanda are also on the roster but haven't been with the team for very long. Taylor is an acceptable Flex option in Week 16.

The 49ers will feature their fourth running back of the season on Sunday against the Dolphins if Guerendo can't suit up. Guerendo was a DNP in Wednesday's practice, but it sounds like the team is already preparing to be without the rookie. It's hard to know what direction the 49ers could go in here, but Patrick Taylor figures to be first in line for touches as the most-tenured member of the Niners. Ke'Shawn Vaughn and Israel Abanikanda only recently joined the team after it was revealed Christian McCaffrey and Jordan Mason would be placed on injured reserve, but both backs could also work into the mix even if Taylor operates as the lead back.