Pierce was listed as questionable on Friday but didn't seem at risk of missing today's game after closing the week with a full practice. With Josh Downs out, Pierce should see a slight uptick in targets, putting him in the WR4 ranks for Week 13. Inactive for the Colts are C Tanor Bortolini, WR Josh Downs, WR Ashton Dulin, QB Sam Ehlinger, FS Darren Hall, DE Isaiah Land, and OT Braden Smith.
Lewis will make his first appearance since injuring his elbow in Week 4 against the Steelers. His addition should be a boon for a Colts front seven that has struggled to pressure the passer in recent weeks. The Colts declared QB Sam Ehlinger, WR Anthony Gould, S Darren Hall, DE Isaiah Land, TE Will Mallory, and LT Bernhard Raimann inactive against the Lions.
Raimann still has not practiced since injuring his knee in practice a couple Wednesdays ago. His Week 13 status is probably up in the air at this point. The rest of this list is the usual inactives for Indianapolis, with three repeats and third quarterback Ehlinger joining Land -- who had played in 10 of 11 games so far for the Colts this year despite just one tackle.