Isaac Guerendo

MCL and ankle sprains RB Isaac Guerendo s MRI this morning showed an MCL sprain and ankle sprain, source said. No ACL damage. (The Athletic - Matt Barrows) FF Today's Take: Guerendo entered Week 18 with foot and hamstring issues. He failed to make it through the first drive in Week 18, ultimately leaving the game for good after two carries. The fourth-rounder's rookie season ends with 84 carries for 420 yards and four touchdowns and 15 catches for 152 yards. Guerendo will likely begin the 2025 season as the No. 3 back again behind Christian McCaffrey and impending restricted free agent Jordan Mason, but he showed enough this season to move ahead of Mason with a strong training camp.

The franchise breathes a collective sigh of relief following the scar incident in the team's Week 18 loss to the Cardinals, which required the cart to take Guerendo from the field. It likely means he will be ready for the start of offseason activities, including organized team activities. Guerendo filled in for the injured Christian McCaffrey and Jordan Mason admirably this season, presenting yet another draft day smash for a franchise known for cashing in on their draft picks.

Guerendo has been diagnosed with MCL and ankle sprains in his left leg following an MRI on Monday, but he didn't damage the ACL in his left knee during Sunday's loss at Arizona, Matt Barrows of The Athletic reports.

Coach Kyle Shanahan said after Sunday's 47-24 loss to the Cardinals that Guerendo (knee/ankle) likely suffered an MCL sprain and will undergo further testing Monday, Lindsey Pallares of the 49ers' official site reports.

Barrows adds that Guerendo will undergo more testing on Monday. Guerendo was dragged down by a defender on his left side, causing Guerendo's left knee to buckle inward. Tomorrow's tests should provide clarity as to the full diagnosis, as well as Guerendo's expected recovery timeline.