Samaje Perine

After going for 8-86-2 in his second game with the Chiefs, Hopkins has totaled just seven receptions for 85 scoreless yards in his last two games. Hopkins' four targets tied with Travis Kelce and Samaje Perine for the second-most on the team, while Xavier Worthy and Noah Gray tied for the team lead with five targets. The splash games will be sporadic for Hopkins in this offense, which makes him difficult to profile as anything more than a WR3 in Week 12 against the Panthers.

The collective Chiefs nation held their breath as Mahomes came up lame following an early fourth quarter touchdown pass to running back Samaje Perine. Mahomes needed assistance to the sideline before being checked by trainers and cleared to return. It turned out to be an aggravation of the ankle injury the franchise quarterback suffered in Week 8, not enough to withhold him from the game in a tied affair. Mahomes would march the team down the field later in the quarter to take a 24-17 lead but watched on the sidelines as Baker Mayfield returned the honor, forcing overtime with just 27 second remaining. The Chiefs won the coin toss and would never give the ball back to Mayfield and the Buccaneers, walking it off on a Kareem Hunt touchdown from two yards out half way through the overtime frame. Mahomes and the Chiefs escaped yet another close call to improve to a perfect 8-0, with their eyes now turned towards the Broncos at home in Week 10.

Perine found the end zone for the first time this season on a Patrick Mahomes scramble drill touchdown in early in the fourth quarter, a play in which Mahomes aggravated an ankle injury he suffered a week prior and had Chiefs' nation holding their collective breath. Mahomes would return and lead two more scoring drives, most of the yardage of which was accounted for by backfield mate Kareem Hunt at the end of the fourth quarter and in overtime. Perine is unlikely to return fantasy value with Hunt seeing workhorse usage, in addition to the eventual return of lead back Isiah Pacheco.

Edwards-Helaire has yet to make his season debut as the team has turned to Kareem Hunt, Samaje Perine, and Carson Steele. Smith-Schuster will miss another week with a hamstring injury sustained in Week 7. Recent acquisition DeAndre Hopkins could see his snap and route participation rates grow in his second game with the team, particularly after a long week. Also inactive for the Chiefs are CB Nazeeh Johnson, OL C.J. Hanson, OT Ethan Driskell, DT Marlon Tuipulotu, and DE Mike Danna.